The Hermia software connects all equipment and staff and helps you reach the full potential of your NM department today and tomorrow. Several items were discussed including the writing of the first article, the development If you wish to receive the OpenDose newsletter, send an email to a new internal dosimetry software for diagnostic nuclear medicine based on the new ICRP adult reference SAF values Run IDAC-Dose2.1 IDAC-Dose has since 1987 been used by the ICRP to estimate effective dose and absorbed doses to patients from radiopharmaceuticals. 47 years of leading SW innovation in NM/MI. Note: STRATOS is an additional module for imalytics sold separately. Key features of the STRATOS Dosimetry Solution: complete workflow for multiple 3D images, including registration, segmentation and visualization calculation of voxel-wise residence-time maps calculation of voxel-wise energy-dose distributions using different approaches: convolution using Dose-Volume-Kernel (DVK), according to MIRD pamphlet 17, supported therapy isotopes: I131, Y90, Lu177, Ho166, Rh188, P32, Sm153 (others on request) support for all SPECT and PET imaging isotopes, enabling both prospective as well as retrospective studies calculation of dose statistics and Dose-Volume-Histograms per region tissue density correction based on the CT scan HTML report with key results and images from the analysis. J. Nucl. Select Nuclear Medicine Exam: Input Injected Activity: mCi or MBq Select Patient Model: Dosimetry Table: Recommended Adult Injected Activity: Minimum: mCi : MBq: Maximum: mCi: MBq : Reference for Adult Injected Activity: Radiation Dose Estimate: VERSION: ADVERTISING LIST SALES . This means that you can adapt the analysis to your clinical workflow and use a combination of 3D scans and planar images, considerably shortening the overall imaging time. The purpose of this guide is to establish a uniform protocol for the placement of radiation dosimeters throughout the Nuclear Medicine department at the University of Iowa Hospitals and Clinics. Nuclear Medicine Communications 2017, vol: 38 (5) pp: 357-365; E. Hippelainen: Voxel-level dosimetry of 177Lu-octreotate: from phantoms to patients, University of Helsinki, Report Series in Physics, 2017, HU-P-D255 Auto-contouring is an essential part of the more holistic solution (MIM SurePlan MRT) designed to automate and standardize every step of your radiopharmaceutical therapy workflow from image acquisition to reporting. For many common radionuclides used in nuclear medicine, the uncertainties in the decay data can be the dominant source of the uncertainty of the S value and should be included in any uncertainty estimation (24). Standalone OLINDA/EXM. MIMcardiac is designed to fit your needs with quick and effective quantitative analysis in one solution. ICRP Publication 128, International Commission on Radiological Protection, The 2007 recommendations of the International Commission on Radiological Protection. Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA 30308, USA . A new website section for performing model-based dosimetry calculations is under development. The OpenDose website is online at www.opendose.org. In this context the, /wp-content/uploads/videos/Video_PLANET_DOSIsoft_update_Theranotics2022_vf.mp4. The generation of dosimetric data represents a computing challenge because of the resources and time required to perform simulations. Since the publication of ICRP Publication 103 (5), the ICRP recommends using voxel-based models, such as those presented in ICRP Report 110 (ICRP 110) (6). This book was released on 2008-01-15 with total page 237 pages. Stress less and rest more with MIMcardiac at your fingertips. In recent years, the market for theranostics has been growing steadily driven in particular by companion diagnostic therapies. On the basis of this dataset, Andersson et al. Note: STRATOS is an additional module for imalytics sold separately, 3D VOI definition on SPECT/CT images for a Lu177-DOTATOC therapy case, 3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Lu177-DOTATOC therapy case, 3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Y90 SIRT case, Registration of a planar scintigraphy image to a 3D CT in Stratos+, Click here to learn more about the possibility of personalized dosimetry with Yttrium 90, Goedicke A, Berker Y, Verburg FA, Behrendt FF, Winz O, Mottaghy FM. Mol. You can find information on the project and collaboration from the documentation section: Czernin, Johannes, et al., The Future of Nuclear Medicine as an Independent Specialty. Czernin, Johannes, et al., The Future of Nuclear Medicine as an Independent Specialty. OpenDose provides data corresponding to the models used in the Monte Carlo simulations, without any mass adjustments, to avoid any calculation approximation or radiation transport simplifications and to maintain a strict framework for data traceability and reproducibility. Nuclear medicine has been largely a diagnostic specialty, and model-derived average organ dose estimates for risk assessment, the traditional application of . Stop by us at the 67th Annual Meeting of the Southwestern Chapter - SNMMI in Texas! J. Nucl. Effective dosimetry, organ and tumor segmentation, deformable registration, and communication tools that help reduce clinical effort are all available in a single solution MIM SurePlan MRT. The collaboration is open to new research teams willing to participate in any OpenDose-related activity, from the production of dosimetric data to the development of the website and dosimetry tools. This means that you can adapt the analysis to your clinical workflow and use a combination of 3D scans and planar images, considerably shortening the overall imaging time. Results are displayed with interactive plots and can be downloaded in a comma-separated values format. 1 where is the mean absorbed dose (Gy) delivered to target tissue, is the total number of nuclear transformations in the source (Bqs), is the mean absorbed dose to a given target per nuclear In the whole-body dosimetry study, the average organ absorbed dose errors were 1.07%, 9.43%, and 34.22% for the CNN, VSV, and OLINDA/EXM dosimetry software, respectively. OpenDose: Open-Access Resource for Nuclear Medicine Dosimetry J Nucl Med. Internal dosimetry in pediatric nuclear medicine. We will get back to you soon. The SAFs for the source Liver were compared with the data published in ICRP 133 (8). Evaluation of voxel-based dosimetry for targeted radionuclide therapies in phantom studies. 6 (2018): 92933. Biomed Phys Eng Express. SAFs are generated through intensive Monte Carlo simulations requiring substantial computational power. Journal of Nuclear Medicine 60, no. Med. MIMneuro's quantitative analysis software makes it easy for you to review your exams and gather your results. HIRD is a straightforward voxel-level internal dosimetry software. This work was supported by the National Measurement System of the U.K. Department for Business, Energy and Industrial Strategy. Benefit from a flexible work environment within the hospital(s) and even from home. By sharing the workload and the computing resources of the teams (https://www.ziemowit.hpc.polsl.pl/en, https://cc.in2p3.fr/en, https://www.calmip.univ-toulouse.fr, and https://nci.org.au), the collaboration can produce data for a model in a few months. If you wish to join the collaboration, please include your activities and potential In particular 2 software developments were MIM SurePlan MRT performs voxel-based absorbed dose calculation using the patient's own anatomy. The last OpenDose collaboration meeting took place in Barcelona the 14th of October 2019 Springer-Verlag, New York. NCINM, the National Cancer Institute dosimetry system for Nuclear Medicine, has been developed to provide accurate dosimetry for patients undergoing nuclear medicine procedures.1-2. A report of adult reference computational phantoms. The aim of the OpenDose project is to establish a long-term international collaboration to generate an open-access database for nuclear medicine dosimetry. MIM SurePlan MRT supports dosimetry for multiple SPECT and PET isotopes, including Lu-177, I-131, I-123, I-124, Cu-64, Cu-67, Ga-68, Ga-67, F-18, In-111, Tc-99m, Sm-153, Sr-89, Sn-117m, Y-90, Ac-225, Ra-223, Pb-212, Re-186, Re-188, and Zr-89. Put MIMcardiac at the heart of your routine. If you want to contact us or ask a question, please fill this form with your name, To help Molecular Imaging processing and MRT optimization in clinical routine, since 2007, DOSIsoft has been leveraging its expertise in Imaging, Radiation Oncology Dosimetry and digital software technologies, to advance Nuclear Medicine for oncology and treatment. The beta version of the OpenDose website has been released and is accessible at Any links to third-party websites that may appear on this site are provided only for your convenience and in no way represent any affiliation or endorsement of the information provided on those linked websites. Our software provides the means for complete and effective treatment analysis and diagnostics. The aim of the OpenDose collaboration is to generate and make freely available a range of dosimetric data and tools. SAFs produced by Monte Carlo simulations are stored in database along with input data. As a consequence, the SAF SDs between the different Monte Carlo codes can reach 65.34% for Brain Liver and electrons of 100 keV and as low as 1.56% at 5 MeV. The ICRP Publication 107 provides electronic data for 1,252 radioisotopes. The initial task set for all partners to produce a set of simulations for a specific model allowed the definition of a common computational framework and the establishment of a unified format for results. Eng. No. 2009. Immediate Open Access: Creative Commons Attribution 4.0 International License (CC BY) allows users to share and adapt with attribution, excluding materials credited to previous publications. Receive updates on upcoming webinars and the latest news from Voximetry. Accurate dosimetry is essential for the safe and effective use of nuclear technology, especially in the medical field. At Hermes Medical Solutions we value the relationship with our customers. This work was performed within the framework of SIRIC LYriCAN Grant INCa-INSERM-DGOS-12563 and LABEX PRIMES (ANR-11-LABX-0063) of Universit de Lyon, within the program Investissements dAvenir (ANR-11-IDEX-0007) operated by the ANR. Some developments to take advantage of large grid infrastructures have also been made (22). The nuclear medicine technologist will then collect three or more nuclear medicine images at different times after the dosimetry administration. OpenDose: Open-Access Resource for Nuclear Medicine Dosimetry, DOI: https://doi.org/10.2967/jnumed.119.240366, Dosimetry-based treatment planning for molecular radiotherapy: a summary of the 2017 report from the Internal Dosimetry Task Force, A generalized schema for radiopharmaceutical dosimetry: standardization of nomenclature. The STRATOS Dosimetry Solution is an advanced research software package for 3D voxelized dose calculation in nuclear medicine, using SPECT/CT and PET/CT data. SPECTRA Recon, featured in MIM Encore, offers a vendor-neutral SPECT reconstruction method, including iterative reconstruction, attenuation correction, energy window-based scatter correction, and resolution recovery. Biomed Phys Eng Express. The quantitative value of 124I PET/CT allows simple and accurate evaluation of lesion dosimetry following medical internal radiation dose formalism and spheres modeling, potentially allowing avoidance of therapeutically ineffective 131I administration. The OpenDose collaboration brings together the resources and expertise of research Considered as a promising and quickly expanding set of therapeutic options for treating many cancer cases, the increment of MRT applications has brought the attention of both the scientific community and the institutional bodies to the need for planning and verification of the absorbed dose delivered to individual patients, as is currently standard practice in External Beam RadioTherapy (EBRT). Mol. Automation is integrated at every step of the process to help nuclear medicine departments capture the therapy opportunity, without sacrificing patient care. This finding is explained by the modification of some target masses in ICRP 133 (Tables A.1 and A.2 from (8)) to add blood content; the original 1.400 kg for the Liver in the ICRP 110 adult female model was changed to 1.810 kg. The program will present exceptional speakers from all over the country who will bring a wealth of knowledge focusing on Theranostics & Future Perspectives, Bringing People to the Field, (Re) Discover & Circulate and Cutting Edge Technology. The adult male is described by 254 127 222 voxels for a size of 2.137 2.137 8.0 mm, corresponding to a height of 1.76 m and a mass of 73 kg. Combine industry-leading therapy response tools for PET with advanced Nuclear Medicine display and processing. A list of 91 energies ranging from 5 keV to 10 MeV was defined on the basis of the logarithmic energy distribution of -emitters in ICRP Publication 107 (13). Through atlas segmentation, you can significantly reduce the time required to generate liver volumes. For answers to questions and other support, join theNCI Hub - Group: NCI Dose Forum. It allows the calculation and visualization of patient-specific dose maps for targeted radionuclide therapies. To assess the variability of results among the different Monte Carlo codes, comparisons were performed using 1 model for a restricted number of sources and energies. Calculated S values were in good agreement with OLINDA/EXM 2.0 (commercial) and IDAC-Dose 2.1 (free) software. Journal of Nuclear Medicine 55, no.1 (2014): 1523. Education material ( lectures and recommended readings ). Why Dosimetry for Radiopharmaceutical Therapy Matters, mpMRI Visualization and Analysis for Prostate. MIM SurePlan MRT provides timesaving tools for organ and tumor segmentation, deformable registration, and voxel-based dosimetry for Molecular Radiotherapy. In particular, when computing resources are not accessible, this task can be performed using precomputed tables of specific absorbed fractions (SAFs) or S values based on dosimetric models. S values are obtained from reference human models and used for model-based dosimetry or adjusted to the geometry of a specific patient (3). Physics models, the use of variance reduction techniques, and any other parameters are the choice of each team. Monte Carlo simulations were performed for monoenergetic photons and electrons. We develop state-of-the-art molecular imaging software into ONE vendor-neutral suite. Contour ProtgAI is a clinically practical auto-contouring solution that uses deep learning algorithms to generate accurate initial results that require minimal editing. But 3D images still new in nuclear medicine and many efforts to improve the spatial distribution of absorbed dose to specific patient anatomy have lead to the development of relative software. Leading innovation in Nuclear Medicine processing, display and analysis for SPECT-CT, PET-CT, PET-MR including dosimetry. In particular, statistical uncertainties of SAFs for Brain Liver are close to 100% at less than 200 keV. Voximetry combines extreme accuracy and exceptional speed with nuclear medicine dosimetry expertise to make personalized radiopharmaceutical therapy clinically feasible. - SNMMI in Texas fit your needs with quick and effective quantitative analysis in one.. Be downloaded in a comma-separated values format steadily driven in particular, statistical uncertainties SAFs... To review your exams and gather your results average organ dose estimates for risk assessment, the market for has. 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